Option1: Install and activate Office 2016 on Mac; Option2: Install and activate Office 2016 on Windows PC; Option1: Install and activate Office 2016 on Mac Way 1 to install Office 2016 on Mac. If your Office 2016 is a new copy and you haven't redeemed the product key or associated it with a Microsoft account, follow these steps: 1. Congratulations, your Office 365 or Office Professional Plus 201..